Browns beat 49ers 19-17, giving Brock Purdy his first start and San Francisco their first loss.

From unstoppable to helpless in the space of a week. The San Francisco 49ers were shown that the NFL has no easy games and no sure things.

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Rookie kicker Jake Moody missed a 41-yard field goal with six seconds remaining, allowing the Cleveland Browns to pull off a shocking 19-17 victory over the San Francisco 49ers on Sunday.

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Nick Bosa, a great defensive end for the 49ers, said, "I don't think we deserved to win." We didn't think they'd be any better than us, but they were. It's more painful because this is our first regular season loss in a very long time.

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The Browns' (3-2) last drive was aided by a controversial unnecessary roughness call against the 49ers, and it was capped by one of Dustin Hopkins' four field goals with 1:40 remaining.

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Deshaun Watson, the team's quarterback, missed his second straight game with a damaged right shoulder, but Cleveland still managed to pull off the upset.

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After beating Dallas 42-10 at home last week and scoring at least 30 points in each of their first five games, the 49ers (5-1) seemed practically unbeatable.

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However, Cleveland's top-ranked defense was more than up to the challenge, and the 49ers' lack of playmakers Christian McCaffrey and Deebo Samuel in the second half was a major factor.

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A perfect 10 for 10 in his professional career, 23-year-old Purdy entered this game with the greatest passer rating (121.1) of any quarterback in league history through 10 games.

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